Bovine Lactoferrin Market Size, Share 2021-2028
Added: (Mon Nov 29 2021)
Pressbox (Press Release) -
Market Overview
The global bovine lactoferrin market size was valued at US$ YY million in 2020 and is estimated to reach US$ YY million by 2028, growing at a CAGR of YY % during the forecast period (2021-2028).
Lactoferrin protein can be found in both human and cow milk. Bovine lactoferrin (bLF) has been shown to have anti-infective, anti-cancer, and anti-inflammatory properties when consumed. Oral bLF, in particular is effective against infections of both digestive and non-digestive tract tissue in a variety of animal models.
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Market Dynamics
The development of the immune system and the benefits associated with bovine lactoferrin are estimated to drive the market.
The development of the immune system is estimated to drive the bovine lactoferrin market
Lactoferrin is regarded to be the most polyvalent protein in vertebrate tissue defence against infections and traumas. It possesses antibacterial capabilities and affects innate and adaptive immune responses due to the proclivity of its basic N-terminal domain to interact with multiple microbial and host targets. Lactoferrin can influence immune cell activation, migration, and proliferation in both positive and negative ways. While lactoferrin's immunomodulatory effects have been demonstrated in vivo utilising lactoferrin deletion, lactoferrin-overexpressing transgenic animals, and dietary lactoferrin, few pathways have been postulated on in vitro research.
While lactoferrin's immunomodulatory effects have been demonstrated in vivo utilising lactoferrin deletion, lactoferrin-overexpressing transgenic mice, and dietary lactoferrin, few mechanisms have been proposed to explain these properties based on in vitro research. Recent studies in humans provided evidence that oral supplementation with lactoferrin contributed to immune stimulation. The lactoferrin-based product increases immunological activities via inducing TGF and Wnt signalling pathways, as well as many genes encoding molecular effectors involved in the innate immune response, according to the study. Lysozymes (which mediate antibacterial defence by cleaving bacterial cell walls), saposins (peptides with antibacterial activity that create ion channels in target cell membranes), and lectins are all members of this gene family (proteins involved in pathogen detection).
The benefits associated with the use of bovine lactoferrin is estimated to drive the market
Bovine lactoferrin (bLF) has been shown to have anti-infective, anti-cancer, and anti-inflammatory properties when consumed. Oral bLF, in particular has shown to be effective against infections of both digestive and non-digestive tract tissue in a variety of animal models. Furthermore, clinical trials on individuals with Helicobacter pylori infection, chronic hepatitis, tinea pedis, and other disorders have shown that bLF has beneficial effects. Immunomodulation in the intestinal and systemic locations may mediate the protective effects of oral bLF against infection.
Recently it was established that oral bLF has antiviral properties in influenza virus-infected mice. The amount of infiltrating leukocytes in the bronchoalveolar lavage fluid was reduced after BLF treatment. Using the quantitative RT-PCR method, oral bLF on the transcription of genes associated with immunity in the small intestine of mice was studied. The expression of IL-12p40, IFN-beta, and NOD2 was observed to be elevated after consuming bLF. As a result, oral bLF promotes the transcription of key immune-related genes in the small intestine, potentially promoting systemic host immunity.
Side effects associated with lactoferrin is estimated to hamper the bovine lactoferrin market
Lactoferrin, in the amounts found in food, is likely safe. Consuming larger levels of lactoferrin up to a year from cow's milk is possibly safe. For up to 14 days, human lactoferrin generated from specifically processed rice appears to be safe. Lactoferrin has the potential to cause diarrhoea. Skin rash, loss of appetite, weariness, cold, and constipation have all been recorded in high doses.
High amounts of lactoferrin can cause diarrhoea, chills, weariness, loss of appetite, and constipation, among other things. People are concerned about mad cow disease since lactoferrin can be obtained from cows. The proper daily dosage of derived from dietary supplements is between 10 and 1200mg. To be safe, seek advice from a healthcare practitioner about a dosage that is appropriate for particular age, health state, and nutritional requirements.
COVID-19 Impact Analysis
Lactoferrin (LF) is a harmless iron-binding glycoprotein found in the milk of most animals. It has antiviral activity across a wide range of viruses, including coronaviruses. LF also has anti-inflammatory, anti-infective, and immune-regulating capabilities in line with SARS-CoV-2 infection therapy requirements. As a result, LF may be useful in the prevention and treatment of COVID-19. Furthermore, compared with other antiviral drugs, LF has a better safety profile. The use of LF may therefore hold promising results in the treatment of COVID-19 and warrants further investigation. Hence, there is an estimated scope for it in the market.
Segment Analysis
By Type
• Spay dried powder*
• Freeze dried powder
By Application
• Infant formula*
• Dietary supplements
• Pharmaceutical
• Others
Geographical Analysis
North America region is estimated to dominate the bovine lactoferrin market
The FDA approval and presence of major key players in this region are estimated to dominate the market.
The US FDA recently cleared lactoferrin for use in infant formula. The demand value of U.S. lactoferrin was about 57.26 tons and is forecasted to increase to about 111.8 tons by 2025. Bovine lactoferrin (bLf) concentration in milk is normally about 100 mg/L (with the range of 70–120 mg/L). Owing to the availability of many cows in this region, the supply of bovine lactoferrin will be more. In the 24 major states the number of milk cows on farms was 8.94 million head 88,000 head more than February 2020, and 2,000 head more than January 2021. In the United States the number of milk cows on farms was 9.46 million, 81,000 head more than February 2020 and 3,000 head more than January 2021. Hence, this region is estimated to dominate the market due to the presence of many cows.
Competitive Landscape
Major key players present in the global bovine lactoferrin market are Fonterra Group, Bega Cheese, FrieslandCampina (DMV), Milei Gmbh, Glanbia Nutritionals, Westland Milk, Tatua, Synlait Milk, WBC, Murray Goulburn and Ingredia Nutritional
Fonterra Group
Overview: Fonterra Cooperative Group is the world's largest dairy exporter, a leader in dairy research and innovation, the owner of a considerable portfolio of Asian Pacific brands, and a partner to many of the world's leading food companies. Fonterra has offices in more than 40 countries across the world with its headquarters in New Zealand.
Product Portfolio: The company comprises Dairy, Nutrition and Dairy Ingredients.
Key Development: In 2020, Fonterra Australia signed an agreement to buy Dairy Country to help the company's premier Australian cheese division become more efficient.
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